Definition
Sublingual or oral lozenge/troche formulations of ketamine, often compounded by specialty pharmacies. Bioavailability is roughly 20-30% compared to IV; commonly used for at-home maintenance treatment under physician supervision.
Related Terms
Ketamine
A dissociative anesthetic developed in the 1960s, now used at sub-anesthetic doses for treatment-resistant depression and other mental health conditions.
Ketamine-Assisted Therapy
A clinical protocol in which sub-anesthetic doses of ketamine are administered (IV, IM, oral, or intranasal) under medical supervision to treat depression, PTSD, anxiety, or chronic pain — typically combined with structured psychotherapy.
Definition is editorial and educational; not a substitute for medical advice. See our Medical Disclaimer.